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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T28290 | Pactimibe | CS 505,CS-505,CS505,Pactimibe free base | |
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity. | |||
T62974 | Pactimibe sulfate | ||
Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor, acting on ACAT1 (IC50: 4.9 μM) and ACAT2 (IC50: 3.0 μM). Pactimibe sulfate inhibited oleoyl-CoA non-competitively (Ki: 5.6 μM) and significantly inhibited cholester... |